fluorine gas

物化性质

外观与性状：

淡黄色气体带有一种辛辣气味

密度：

1.695（15℃）

熔点：

-220°C

沸点：

-188°C

水溶解性：

reacts

折射率：

1.000195

存储条件/存储方法：

库房通风低温干燥,轻装轻卸

稳定性相关：

1.氟是最活泼的非金属元素，几乎可与所有的元素直接化合。与水反应生成臭氧和氟化氢。在暗处就能与氢直接化合。在室温下能与大多数可氧化物质或有机物强烈反应而燃烧，与硝酸反应能生成爆炸性的硝酸氟气体。腐蚀性强，剧毒！

2.稳定性^[14] 稳定

3.禁配物^[15] 易燃或可燃物、活性金属粉末、氨、联胺等

4.聚合危害^[16] 不聚合

其它信息：

1.性状：淡黄色气体，有刺激性气味。^[1]

2.熔点（ºC）：-219^[2]

3.沸点（ºC）：-188^[3]

4.相对密度（水=1）：1.14（-200℃）^[4]

5.相对蒸气密度（空气=1）：1.695^[5]

6.饱和蒸气压（kPa）：0.133（-223ºC）^[6]

7.临界温度（℃）：-129^[7]

8.临界压力（MPa）：5.57^[8]

9.辛醇/水分配系数：0.22^[9]

10.溶解性：与水反应。^[10]

安全信息

外观与性状：

淡黄色气体带有一种辛辣气味

密度：

1.695（15℃）

熔点：

-220°C

沸点：

-188°C

水溶解性：

reacts

折射率：

1.000195

存储条件/存储方法：

库房通风低温干燥,轻装轻卸

稳定性相关：

1.氟是最活泼的非金属元素，几乎可与所有的元素直接化合。与水反应生成臭氧和氟化氢。在暗处就能与氢直接化合。在室温下能与大多数可氧化物质或有机物强烈反应而燃烧，与硝酸反应能生成爆炸性的硝酸氟气体。腐蚀性强，剧毒！

2.稳定性^[14] 稳定

3.禁配物^[15] 易燃或可燃物、活性金属粉末、氨、联胺等

4.聚合危害^[16] 不聚合

其它信息：

1.性状：淡黄色气体，有刺激性气味。^[1]

2.熔点（ºC）：-219^[2]

3.沸点（ºC）：-188^[3]

4.相对密度（水=1）：1.14（-200℃）^[4]

5.相对蒸气密度（空气=1）：1.695^[5]

6.饱和蒸气压（kPa）：0.133（-223ºC）^[6]

7.临界温度（℃）：-129^[7]

8.临界压力（MPa）：5.57^[8]

9.辛醇/水分配系数：0.22^[9]

10.溶解性：与水反应。^[10]

毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :

LM6475000

CHEMICAL NAME :

Fluorine

CAS REGISTRY NUMBER :

7782-41-4

LAST UPDATED :

199712

DATA ITEMS CITED :

46

MOLECULAR FORMULA :

F2

MOLECULAR WEIGHT :

38.00

WISWESSER LINE NOTATION :

E2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Human

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rat

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - mouse

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Mammal - dog

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968 ** ACUTE TOXICITY DATA **

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

185 ppm/1H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - conjunctive irritation Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

150 ppm/1H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - iritis Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968

TYPE OF TEST :

LC - Lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

>93 ppm/1H

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - cough Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - nausea or vomiting

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

270 ppm/30M

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - iritis Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

170 ppm/1H

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 29,10,1968 *** REVIEWS *** ACGIH TLV-STEL 3.1 mg/m3 (2 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 1.6 mg/m3 (1 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW JAVMA4 Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915- Volume(issue)/page/year: 164,277,1974 TOXICOLOGY REVIEW FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ. Volume(issue)/page/year: 7,313,1942 TOXICOLOGY REVIEW KOTTAM Kogai to Taisaku. Journal of Environmental Pollution Control. (Kogai Taisaku Gijutsu Dokokai, Shuwa-Akasaka Bldg., 9-1-244, Akasaka, Minato-ku, Tokyo 107, Japan) V.1- 1965- Volume(issue)/page/year: 11,1300,1975 TOXICOLOGY REVIEW CLCHAU Clinical Chemistry (Winston-Salem, NC). (American Assoc. for Clinical Chemistry, 1725 K St., NW, Washington, DC 20006) V.1- 1955- Volume(issue)/page/year: 19,361,1973 TOXICOLOGY REVIEW AJMEAZ American Journal of Medicine. (Technical Pub., 875 Third Ave., New York, NY 10022) V.1- 1946- Volume(issue)/page/year: 38,409,1965 TOXICOLOGY REVIEW IECHAD Industrial and Engineering Chemistry. (Washington, DC) V.15-62, 1923-70. For publisher information, see CHMTBL. Volume(issue)/page/year: 26,791,1934 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 ppm (2 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,117,1971 OSHA PEL (Gen Indu):8H TWA 0.1 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 ppm (0.2 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.1 ppm (0.2 mg/m3) JAN 1993 OEL-AUSTRALIA:TWA 1 ppm (2 mg/m3);STEL 2 ppm (4 mg/m3) JAN 1993 OEL-BELGIUM:TWA 1 ppm (1.6 mg/m3);STEL 2 ppm (3.1 mg/m3) JAN 1993 OEL-DENMARK:TWA 0.1 ppm (0.2 mg/m3) JAN 1993 OEL-FINLAND:STEL 0.1 ppm (0.26 mg/m3) JAN 1993 OEL-FRANCE:STEL 1 ppm (2 mg/m3) JAN 1993 OEL-GERMANY:TWA 0.1 ppm (0.2 mg/m3) JAN 1993 OEL-HUNGARY:TWA 0.2 mg/m3;STEL 0.4 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 1 ppm (2 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 ppm (0.2 mg/m3) JAN 1993 OEL-POLAND:TWA 0.05 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 ppm (0.2 mg/m3);STEL 0.3 ppm (0.5 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 0.1 ppm (0.15 mg/m3);STEL 0.2 ppm JAN 1993 OEL-THAILAND:TWA 0.1 ppm (0.2 mg/m3) JAN 1993 OEL-TURKEY:TWA 0.1 ppm (0.2 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 1 ppm (2 mg/m3);STEL 2 ppm (4 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO FLUORINE-air:10H TWA 0.1 ppmREFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 33370 No. of Facilities: 396 (estimated) No. of Industries: 10 No. of Occupations: 13 No. of Employees: 2580 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 33370 No. of Facilities: 490 (estimated) No. of Industries: 19 No. of Occupations: 25 No. of Employees: 12854 (estimated) No. of Female Employees: 2059 (estimated)

毒理学数据：

1.急性毒性^[11]LC50：233mg/m³（大鼠吸入，1h）

2.刺激性^[12]人经眼：25ppm（5min），轻度刺激。

3.亚急性与慢性毒性^[13]小鼠、豚鼠、兔和狗分别吸入25，8，3，0.8mg/m³，35d，动物死亡率＜40%，尸检见支气管炎、支气管扩张、肺出血、肺水肿。

生态数据：

1.生态毒性 暂无资料

2.生物降解性 暂无资料

3.非生物降解性 暂无资料

MSDS

第一部分：化学品名称

分子结构与计算化学数据

分子结构数据

1、摩尔折射率：2.37

2、摩尔体积（cm³/mol）：39.4

3、等张比容（90.2K）：51.1

4、表面张力（dyne/cm）：2.8

5、介电常数：无可用的

6、极化率：0.94

7、单一同位素质量：37.996806 Da

8、标称质量：38 Da

9、平均质量：37.9968 Da

计算化学数据

1、疏水参数计算参考值（XlogP）：1.1

2、氢键供体数量：0

3、氢键受体数量：2

4、可旋转化学键数量：0

5、互变异构体数量：无

6、拓扑分子极性表面积（TPSA）：0

7、重原子数量：2

8、表面电荷：0

9、复杂度：0

10、同位素原子数量：0

11、确定原子立构中心数量：0

12、不确定原子立构中心数量：0

13、确定化学键立构中心数量：0

14、不确定化学键立构中心数量：0

15、共价键单元数量：1