8H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one,5,6-dihy
- 中文别名：BERLAMBINE
- 中文释义：小檗浸碱;氧化小蘖碱;BERLAMBINE
- 英文别名：Oxyberberine;
berberin-8-one;
Berlambine;
8-oxoberberine;
Ketoberberine
- cas No.：549-21-3
- 分子式：C20H17NO5
- 分子量：351.35
- 精确分子量：351.11100
- PSA：58.92000
- InChI：The Key: ZHYQCBCBTQWPLC-UHFFFAOYSA-N
- 分子结构式：
物化性质
- 密度：
- 1.44g/cm3
- 熔点：
- 200-201ºC
- 沸点：
- 611.5ºC at 760mmHg
- 闪点：
- 323.6ºC
- 折射率：
- 1.691
安全信息
- 密度：
- 1.44g/cm3
- 熔点：
- 200-201ºC
- 沸点：
- 611.5ºC at 760mmHg
- 闪点：
- 323.6ºC
- 折射率：
- 1.691
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DS0180000
- CHEMICAL NAME :
- 8-Berbinone, 13,13a-didehydro-9,10-dimethoxy-2,3-(methylenedioxy)-
- CAS REGISTRY NUMBER :
- 549-21-3
- BEILSTEIN REFERENCE NO. :
- 0339209
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C20-H17-N-O5
- MOLECULAR WEIGHT :
- 351.38
- WISWESSER LINE NOTATION :
- T G5 D6 C666 HO JO ONV IH&&T&&J RO1 SO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 15,486,1981