- 中文别名：血色素
- 中文释义：羟高铁血红素;高铁血红素;血色素
- 英文别名：hematin;
phenodin;
HEMATIN;
ferriprotoporphyrin IX hydroxide;
BOVINE HEMIN;
HAEMATIN;
ferrihemate;
heme;
ferriprotoporphyrin IX;
Hematin porcine;
HO-Fe(III)(protoporphyrin);
ferriheme;
haem - cas No.：15489-90-4
- 分子式：
C34H31FeN4O5.2H
- 分子量：633.50
- 精确分子量：633.18000
- PSA：129.41000
- MDL：MFCD00011615
- InChI：InChI=1/C34H34N4O4.Fe.H2O/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);;1H2/q;+2;/p-2/b25-13-,26-13-,27-14-
- 分子结构式：
物化性质
- 外观与性状：
- 暗晶体带有金属光泽
- 熔点：
- 180ºC
- 沸点：
- 1128.5ºC at 760 mmHg
- 闪点：
- 636.3ºC
- 蒸汽压：
- 0mmHg at 25°C
- 存储条件/存储方法：
- 稳定性相关：
常温常压下稳定
避免的物料： 氧化物- 其它信息：
安全信息
- 外观与性状：
- 暗晶体带有金属光泽
- 熔点：
- 180ºC
- 沸点：
- 1128.5ºC at 760 mmHg
- 闪点：
- 636.3ºC
- 蒸汽压：
- 0mmHg at 25°C
- 存储条件/存储方法：
- 稳定性相关：
常温常压下稳定
避免的物料： 氧化物- 其它信息：
毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NO6725000
- CHEMICAL NAME :
- Iron, (dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2,18-porphinedipro pionato(2-))-hydroxy-
- CAS REGISTRY NUMBER :
- 15489-90-4
- LAST UPDATED :
- 199106
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C34-H31-Fe-N4-O5.2H
- MOLECULAR WEIGHT :
- 633.56
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 40 mg/kg/30D-I
- TOXIC EFFECTS :
- Cardiac - pulse rate increase, without fall in BP Vascular - BP elevation not characterized in autonomic section Nutritional and Gross Metabolic - body temperature increase
- REFERENCE :
- AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 101,877,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 43 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - hemorrhage
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 2,329,1978
- 毒理学数据：
急性毒性：小鼠静脉LD50:43mg/kg
- 生态数据：
MSDS
| Name: | HEMATIN FROM BOVINE BLOOD Material Safety Data Sheet |
| Synonym: | |
| CAS: | 15489-90-4 |
Synonym:
Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
| CAS# | Chemical Name | content | EINECS# |
| 15489-90-4 | HEMATIN, FROM BOVINE BLOOD | 239-518-9 |
Risk Phrases: None Listed.
Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Not available.
Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.
Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.
Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 15489-90-4: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Solid
Color: black
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula:
Molecular Weight:
Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Unstable.
Conditions to Avoid:
Not available.
Incompatibilities with Other Materials:
Not available.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, carbon dioxide.
Hazardous Polymerization: Will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 15489-90-4: NO6725000 LD50/LC50:
Not available.
Carcinogenicity:
HEMATIN, FROM BOVINE BLOOD - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
Section 12 - ECOLOGICAL INFORMATION
Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.
Section 14 - TRANSPORT INFORMATION
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
Section 15 - REGULATORY INFORMATION
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 15489-90-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 15489-90-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 15489-90-4 is not listed on the TSCA inventory.
It is for research and development use only.
SECTION 16 - ADDITIONAL INFORMATION
N/A